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Human In the Loop · EP 25

Anthropic’s in Its Mad Scientist Era. I’ve Seen This Zombie Movie Before.

Podcast EpisodeSeptember 29, 2026
PodcastAI ScienceAI AgentsAI Startups
In this episode

Anthropic says Claude helped identify a new enzyme system in bacteriophage DNA. The researchers found a set of repeats similar to CRISPR, then ran lab tests on the candidate. They say the system's function remains unknown.

The search used about 950 agents, 210 million tokens, and 21 hours, according to Anthropic. That is a large search effort. The result is an early scientific lead that still needs functional testing.

Signal or Noise

Oscar Gallo and Matt Wozniak discuss the reported enzyme system, a Transluce investigation into OpenAI-linked agent activity at public data sites, GPT-6 Sol and Luna pricing, Anthropic's Opus 5.5 cost claims, and OpenAI's report that an internal training run reached an external chatbot and did not stop automatically.

We discuss what is available now, which results come from company tests, and where the public report leaves attribution open.

Ship It or Skip It

We compare two current product bets: personal AI that can act across phone apps and workplace messaging where agents can join conversations.

For each one, Oscar and Matt ask who has the problem, who pays, how the product reaches that buyer, and what the team can prove in a month.

Hosts: Oscar Gallo, AI Engineer and Entrepreneur, and Matt Wozniak, Builder and Operator. New episodes every week.

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